Carlos had a great time catching up with collaborators Sami Barmada, Lisa Sharkey and Magda Ivanova as well as sharing our latest work on UBQLN2 at the Gateway NMR Meeting!
Peter, a new first-year biology graduate student, joins the lab for his first rotation. He will be studying UBQLN2 droplet properties.
We are very excited for this collaborative work looking at how ALS-linked mutations affect the structure, oligomerization and LLPS properties of UBQLN2. Read the paper here.
We made 95 UBQLN2 variants to determine the site- and residue-specific effects on LLPS and found quite a few beautiful trends. Read more here.
Yiran Yang, a third-year grad student, was selected to present a talk, and Holly Jones, a first-year grad student, presented a poster on UBQLN2. Congratulations to both!
Junior undergraduate Julia Riley and postdoc Thuy Dao wrote a preview on the Mittag group’s work on liquid phase separation of SPOP, a substrate adaptor protein for cullin3-RING ubiquitin E3 ligase, and its ubiquitination substrates. See our preview Riley et al. – 2018 and a link to the original paper here.
We received this award to continue our studies of ubiquilin phase separation. Read more about the award here.
We have been very busy over the last year. Revamped lab research pages are forthcoming…
Over the summer, the lab received two awards: a Ralph E. Powe Junior Faculty Enhancement Award towards work on a ubiquitin-like protein, and an ALS Association starter grant for work on the ubiquilin protein, known to mediate both proteasome-mediated degradation and autophagy processes in the cell.
See the full story here!
Freshman Yona Lei has just received a SU Biology fellowship to conduct summer research in our lab. Congratulations Yona!